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GC7 Sulfate

CAS No. 150417-90-6

GC7 Sulfate( —— )

Catalog No. M32934 CAS No. 150417-90-6

GC7 Sulfate is a potent inhibitor of deoxyhypusine synthase (DHS). Eukaryotic translation initiation factor 5A2 (eIF5A2) is the only known substrate for DHS, so GC7 inhibits the activation of eIF5A2 by inhibiting DHS activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 85 In Stock
25MG 187 In Stock
50MG 276 In Stock
100MG 445 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    GC7 Sulfate
  • Note
    Research use only, not for human use.
  • Brief Description
    GC7 Sulfate is a potent inhibitor of deoxyhypusine synthase (DHS). Eukaryotic translation initiation factor 5A2 (eIF5A2) is the only known substrate for DHS, so GC7 inhibits the activation of eIF5A2 by inhibiting DHS activity.
  • Description
    GC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    Autophagy
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    150417-90-6
  • Formula Weight
    270.35
  • Molecular Formula
    C8H22N4O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 3 mg/mL (11.10 mM)
  • SMILES
    O=S(=O)(O)O.N=C(N)NCCCCCCCN
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bandino A, et al. Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients. Cell Oncol (Dordr). 2014 Dec;37(6):387-98.?
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