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Graveoline

CAS No. 485-61-0

Graveoline( 2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one | Foliosine )

Catalog No. M24439 CAS No. 485-61-0

Graveoline is an apoptosis and autophagy inducer in skin melanoma cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 44 In Stock
5MG 40 In Stock
10MG 57 In Stock
25MG 93 In Stock
50MG 133 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Graveoline
  • Note
    Research use only, not for human use.
  • Brief Description
    Graveoline is an apoptosis and autophagy inducer in skin melanoma cancer cells.
  • Description
    Graveoline is an apoptosis and autophagy inducer in skin melanoma cancer cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one | Foliosine
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    autophagy
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    485-61-0
  • Formula Weight
    279.29
  • Molecular Formula
    C17H13NO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CN1C2=CC=CC=C2C(=O)C=C1C3=CC4=C(C=C3)OCO4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ghosh S, Bishayee K, Khuda-Bukhsh AR. Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic signaling pathway. Phytother Res. 2014;28(8):1153-1162. doi:10.1002/ptr.5107
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