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AUTEN-99

CAS No. 904054-02-0

AUTEN-99( —— )

Catalog No. M16499 CAS No. 904054-02-0

A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy.

Purity : >98% (HPLC)

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Biological Information

Product Name

AUTEN-99
Note

Research use only, not for human use.
Brief Description

A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy.
Description

A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy; induces autophagic flux and promotes cell survival in mammalian cell cultures; increases the number of autophagic structures in mice and Drosophila, and effectively penetrates through a blood-brain barrier model; impedes the progression of neurodegenerative symptoms in Drosophila models of Parkinson's and Huntington's diseases.
In Vitro

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In Vivo

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Synonyms

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Pathway

Autophagy
Target

Autophagy
Recptor

Autophagy
Research Area

——
Indication

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Chemical Information

CAS Number

904054-02-0
Formula Weight

278.373
Molecular Formula

C17H14N2S
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

2-([1,1'-biphenyl]-4-yl)-5,6-dihydroimidazo[2,1-b]thiazole

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Kovács T, et al. Sci Rep. 2017 Feb 16;7:42014.

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