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3-O-Methylgallic acid

CAS No. 3934-84-7

3-O-Methylgallic acid( 3,4-Dihydroxy-5-methoxybenzoic acid | 3,4-Dihydroxy-5-methoxybenzoic acid )

Catalog No. M29069 CAS No. 3934-84-7

3,4-Dihydroxy-5-methoxybenzoic acid reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3,4-Dihydroxy-5-methoxybenzoic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    3-O-Methylgallic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    3,4-Dihydroxy-5-methoxybenzoic acid reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3,4-Dihydroxy-5-methoxybenzoic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer.
  • Description
    3,4-Dihydroxy-5-methoxybenzoic acid reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3,4-Dihydroxy-5-methoxybenzoic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer.(In Vitro):3,4-Dihydroxy-5-methoxybenzoic acid(10-100 μM) caused a time- and dose-dependent decrease in cell viability.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    3,4-Dihydroxy-5-methoxybenzoic acid | 3,4-Dihydroxy-5-methoxybenzoic acid
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3934-84-7
  • Formula Weight
    184.147
  • Molecular Formula
    C8H8O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (271.52 mM)
  • SMILES
    COc1cc(cc(O)c1O)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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