Tubulin polymerization-IN-43( —— )

Catalog No. M37016 CAS No. 2773345-90-5

Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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5MG	330	Get Quote
10MG	468	Get Quote
25MG	751	Get Quote
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Biological Information

Product Name

Tubulin polymerization-IN-43
Note

Research use only, not for human use.
Brief Description

Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.
Description

Tubulin polymerization-IN-43 (compound 15h) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-43 disrupts cellular microtubule networks by targeting the Colchicine (HY-16569) site, and promots cell cycle arrest of leukemia cells at G2/M phase and cell apoptosis, as well as inhibiting angiogenesis.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

Apoptosis
Recptor

Apoptosis | Microtubule Associated
Research Area

——
Indication

——

Chemical Information

CAS Number

2773345-90-5
Formula Weight

351.3
Molecular Formula

C17H13F4N3O
Purity

>98% (HPLC)
Solubility

——
SMILES

N(C)(C=1C2=C(N=C(C(F)(F)F)N1)C=CC(F)=C2)C3=CC=C(OC)C=C3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Wu H, et, al. Discovery of novel N-aryl-2-trifluoromethyl-quinazoline-4-amine derivatives as the inhibitors of tubulin polymerization in leukemia cells. Eur J Med Chem. 2023 Aug 5;256:115470.?

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