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Tubulin polymerization-IN-43

CAS No. 2773345-90-5

Tubulin polymerization-IN-43( —— )

Catalog No. M37016 CAS No. 2773345-90-5

Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 139 In Stock
10MG 197 In Stock
25MG 326 In Stock
50MG 421 In Stock
100MG 578 In Stock
200MG 775 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Tubulin polymerization-IN-43
  • Note
    Research use only, not for human use.
  • Brief Description
    Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.
  • Description
    Tubulin polymerization-IN-43 (compound 15h) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-43 disrupts cellular microtubule networks by targeting the Colchicine (HY-16569) site, and promots cell cycle arrest of leukemia cells at G2/M phase and cell apoptosis, as well as inhibiting angiogenesis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis | Microtubule Associated
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2773345-90-5
  • Formula Weight
    351.3
  • Molecular Formula
    C17H13F4N3O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(C)(C=1C2=C(N=C(C(F)(F)F)N1)C=CC(F)=C2)C3=CC=C(OC)C=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wu H, et, al. Discovery of novel N-aryl-2-trifluoromethyl-quinazoline-4-amine derivatives as the inhibitors of tubulin polymerization in leukemia cells. Eur J Med Chem. 2023 Aug 5;256:115470.?
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