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Home - Products - Proteasome/Ubiquitin - DUB - HBX 41108

HBX 41108

CAS No. 924296-39-9

HBX 41108( HBX-41108 )

Catalog No. M27424 CAS No. 924296-39-9

HBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 80 In Stock
5MG 73 In Stock
10MG 117 In Stock
25MG 235 In Stock
50MG 368 In Stock
100MG 554 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    HBX 41108
  • Note
    Research use only, not for human use.
  • Brief Description
    HBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
  • Description
    HBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    HBX-41108
  • Pathway
    Proteasome/Ubiquitin
  • Target
    DUB
  • Recptor
    Bax|Bcl-2|Caspase-3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    924296-39-9
  • Formula Weight
    266.64
  • Molecular Formula
    C13H3ClN4O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (937.59 mM)
  • SMILES
    Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhou D, et al. Antiproliferative steroidal glycosides from rhizomes of Polygonatum sibiricum. Phytochemistry. 2019;164:172-183.
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