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Dimethindene maleate
CAS No. 3614-69-5
Dimethindene maleate( SU 6518 | SU-6518 | UNII-6LL60J9E0O | Dimethindene maleate )
Catalog No. M27412 CAS No. 3614-69-5
Dimethindene maleate is a histamine H1 antagonist and can be used in studies about the treatment of hypersensitivity reactions, pruritus and rhinitis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 87 | In Stock |
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| 10MG | 140 | In Stock |
|
| 25MG | 295 | In Stock |
|
| 50MG | 475 | In Stock |
|
| 100MG | 692 | In Stock |
|
| 500MG | 1422 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDimethindene maleate
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NoteResearch use only, not for human use.
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Brief DescriptionDimethindene maleate is a histamine H1 antagonist and can be used in studies about the treatment of hypersensitivity reactions, pruritus and rhinitis.
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DescriptionDimethindene maleate is a histamine H1 antagonist and can be used in studies about the treatment of hypersensitivity reactions, pruritus and rhinitis.
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In VitroDimethindene maleate (1-1000 μM) suppresses the cromakalim-induced/glibenclamide-sensitive K＋ currents in a concentration-dependent and reversible manner with an IC50 value of 29.5 μM.Dimethindene maleate (1-1000 μM) inhibits Y-26763-induced glibenclamide-sensitive K＋ currents with an IC50 value of 49 μM.
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In VivoDimethindene maleate (0.25 mg; i.p. once) affects wound healing in mice. Animal Model:C57BL/6 mice with wound healing Dosage:0.25 mg Administration:Intraperitoneal injection; 0.25 mg once Result:Significantly delayed skin wound and only showed wound closure impairment in the initial phase wound healing.
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SynonymsSU 6518 | SU-6518 | UNII-6LL60J9E0O | Dimethindene maleate
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PathwayGPCR/G Protein
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TargetHistamine Receptor
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number3614-69-5
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Formula Weight408.49
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Molecular FormulaC24H28N2O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (306.01 mM)
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SMILESC1(=C(Cc2c1cccc2)CCN(C)C)[C@@H](c1ncccc1)C.C(\C=C/C(=O)O)(=O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.K D Brunnemann, et al. N-Nitrosomorpholine and Other Volatile N-nitrosamines in Snuff Tobacco. Carcinogenesis. 1982;3(6):693-6.
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