hDHODH-IN-1

CAS No. 1173715-42-8

hDHODH-IN-1( —— )

Catalog No. M26247 CAS No. 1173715-42-8

hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 71 In Stock
5MG 65 In Stock
10MG 105 In Stock
25MG 211 In Stock
50MG 300 In Stock
100MG 418 In Stock
200MG 564 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    hDHODH-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.
  • Description
    hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.(In Vitro):Dihydroorotate dehydrogenase (DHODH) is a class-2 dihydroorotate dehydrogenase in human. Inhibitors have been developed to eliminate human DHODH (hDHODH) activity, which is associated with cancers,inflammatory diseases , and autoimmune and multiple sclerosis because DHODH is required to ensure proliferating-cell viability.
  • In Vitro
    Human dihydroorotate dehydrogenase (hDHODH) is a class-2 dihydroorotate dehydrogenase. Because DHODH is required to ensure proliferating-cell viability, inhibitors have been developed to eliminate human DHODH (hDHODH) activity, which is associated with cancers, multiple sclerosis, and autoimmune and inflammatory diseases.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    PEGs
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1173715-42-8
  • Formula Weight
    278.311
  • Molecular Formula
    C17H14N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (898.28 mM)
  • SMILES
    C\C(O)=C(/C#N)C(=O)Nc1ccc(cc1)-c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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