hDHODH-IN-1

Research use only, not for human use.

hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.

hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.(In Vitro):Dihydroorotate dehydrogenase (DHODH) is a class-2 dihydroorotate dehydrogenase in human. Inhibitors have been developed to eliminate human DHODH (hDHODH) activity, which is associated with cancers,inflammatory diseases , and autoimmune and multiple sclerosis because DHODH is required to ensure proliferating-cell viability.

Human dihydroorotate dehydrogenase (hDHODH) is a class-2 dihydroorotate dehydrogenase. Because DHODH is required to ensure proliferating-cell viability, inhibitors have been developed to eliminate human DHODH (hDHODH) activity, which is associated with cancers, multiple sclerosis, and autoimmune and inflammatory diseases.

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Metabolic Enzyme/Protease

Dehydrogenase

PEGs

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1173715-42-8

278.311

C17H14N2O2

>98% (HPLC)

In Vitro:?DMSO : 250 mg/mL (898.28 mM)

C\C(O)=C(/C#N)C(=O)Nc1ccc(cc1)-c1ccccc1

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(-20℃)

With Ice Pack

≥ 2 years