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Tiazofurin

CAS No. 60084-10-8

Tiazofurin( NSC 286193 | Riboxamide )

Catalog No. M28325 CAS No. 60084-10-8

Tiazofurin is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH) .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Tiazofurin
  • Note
    Research use only, not for human use.
  • Brief Description
    Tiazofurin is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH) .
  • Description
    Tiazofurin is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH) .
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC 286193 | Riboxamide
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    Antifungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    60084-10-8
  • Formula Weight
    260.26
  • Molecular Formula
    C9H12N2O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    NC(=O)c1csc(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Moraes DC, et al. β-lapachone and α-nor-lapachone modulate Candida albicans viability and virulence factors. J Mycol Med. 2018 Mar 26. pii: S1156-5233(17)30379-7.
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