Indophagolin( —— )

Catalog No. M23377 CAS No. 1207660-00-1

Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	87	In Stock
5MG	75	In Stock
10MG	119	In Stock
25MG	199	In Stock
50MG	269	In Stock
100MG	379	In Stock
200MG	513	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Indophagolin
Note

Research use only, not for human use.
Brief Description

Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM.
Description

Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively.
In Vitro

Indophagolin (10 μM) inhibits autophagosome formation in MCF7 cells.
In Vivo

——
Synonyms

——
Pathway

Autophagy
Target

Autophagy
Recptor

autophagy|P2X1|P2X3|P2X4
Research Area

——
Indication

——

Chemical Information

CAS Number

1207660-00-1
Formula Weight

523.75
Molecular Formula

C19H15BrClF3N2O3S
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

O=S(C1=CC2=C(C=C1Br)CCN2C(C3CC3)=O)(NC4=CC=C(Cl)C(C(F)(F)F)=C4)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Carnero Corrales MA, et al. Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin [published online ahead of print, 2021 Mar 9]. Cell Chem Biol. 2021;S2451-9456(21)00102-1.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks