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Indophagolin
CAS No. 1207660-00-1
Indophagolin( —— )
Catalog No. M23377 CAS No. 1207660-00-1
Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 142 | In Stock |
|
| 5MG | 210 | In Stock |
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| 10MG | 316 | In Stock |
|
| 25MG | 534 | In Stock |
|
| 50MG | 761 | In Stock |
|
| 100MG | 1053 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameIndophagolin
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NoteResearch use only, not for human use.
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Brief DescriptionIndophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM.
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DescriptionIndophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively.
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In VitroIndophagolin (10 μM) inhibits autophagosome formation in MCF7 cells.
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetAutophagy
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Recptorautophagy|P2X1|P2X3|P2X4
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Research Area——
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Indication——
Chemical Information
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CAS Number1207660-00-1
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Formula Weight523.75
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Molecular FormulaC19H15BrClF3N2O3S
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESO=S(C1=CC2=C(C=C1Br)CCN2C(C3CC3)=O)(NC4=CC=C(Cl)C(C(F)(F)F)=C4)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Carnero Corrales MA, et al. Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin [published online ahead of print, 2021 Mar 9]. Cell Chem Biol. 2021;S2451-9456(21)00102-1.
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