Cart
sales@molnova.com
ULK-101
CAS No. 2443816-45-1
ULK-101( —— )
Catalog No. M24125 CAS No. 2443816-45-1
ULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 264 | In Stock |
|
| 2MG | 152 | In Stock |
|
| 5MG | 261 | In Stock |
|
| 10MG | 410 | In Stock |
|
| 25MG | 696 | In Stock |
|
| 50MG | 949 | In Stock |
|
| 100MG | 1302 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameULK-101
-
NoteResearch use only, not for human use.
-
Brief DescriptionULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
-
DescriptionULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
-
In VitroULK-101 (0-5 μM) reduces BafA1-induced LC3B-II accumulation in U2OS cells in a concentration-dependent manner.
-
In Vivo——
-
Synonyms——
-
PathwayAutophagy
-
TargetAutophagy
-
RecptorULK1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2443816-45-1
-
Formula Weight460.4
-
Molecular FormulaC22H16F4N4OS
-
Purity>98% (HPLC)
-
SolubilityDMSO:84mg/mL (182.43mM)
-
SMILESO=C(C1=CC(C2=C3N=CC(C4=CC=C(F)C=C4)=CN3N=C2)=CS1)N[C@@H](C5CC5)C(F)(F)F
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Martin KR, Celano SL, Solitro AR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. iScience. 2018;8:74-84. doi:10.1016/j.isci.2018.09.012
molnova catalog
related products
-
Cysteamine hydrochlo...
An agent for the treatment of nephropathic cystinosis and an antioxidant; increases intracellular glutathione levels in cystinotic cells, also increases the rates of apoptosis in cystinotic cells.
-
ATG7-IN-1
ATG7-IN-1 is a selective ATG7 inhibitor with an IC50 of 62 nM.
-
PD146176
PD146176 is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.?PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice.
