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ULK-101

CAS No. 2443816-45-1

ULK-101( —— )

Catalog No. M24125 CAS No. 2443816-45-1

ULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 218 In Stock
5MG 335 In Stock
10MG 537 In Stock
25MG 842 In Stock
50MG 1134 In Stock
100MG 1521 In Stock
500MG 3042 In Stock
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Biological Information

  • Product Name
    ULK-101
  • Note
    Research use only, not for human use.
  • Brief Description
    ULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
  • Description
    ULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
  • In Vitro
    ULK-101 (0-5 μM) reduces BafA1-induced LC3B-II accumulation in U2OS cells in a concentration-dependent manner.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    ULK1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2443816-45-1
  • Formula Weight
    460.4
  • Molecular Formula
    C22H16F4N4OS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:84mg/mL (182.43mM)
  • SMILES
    O=C(C1=CC(C2=C3N=CC(C4=CC=C(F)C=C4)=CN3N=C2)=CS1)N[C@@H](C5CC5)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Martin KR, Celano SL, Solitro AR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. iScience. 2018;8:74-84. doi:10.1016/j.isci.2018.09.012
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