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Tesmilifene fumarate
CAS No. 1185241-83-1
Tesmilifene fumarate( DPPE fumarate )
Catalog No. M23352 CAS No. 1185241-83-1
Tesmilifene fumarate (DPPE fumarate) is an H1C receptor antagonist。
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
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| 5MG | 37 | In Stock |
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| 10MG | 55 | In Stock |
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| 25MG | 112 | In Stock |
|
| 50MG | 164 | In Stock |
|
| 100MG | 244 | In Stock |
|
| 200MG | 361 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTesmilifene fumarate
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NoteResearch use only, not for human use.
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Brief DescriptionTesmilifene fumarate (DPPE fumarate) is an H1C receptor antagonist。
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DescriptionTesmilifene fumarate (DPPE fumarate) is an H1C receptor antagonist。
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In VitroTesmilifene may modulate the effects of 12(S)HETE in cancer cells, and indirectly, influence the susceptibility of cellular DNA to chemotherapy.
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In VivoTesmilifene (DPPE, 20 mg/kg (s.c.) and 20 μg (icv in 5 μL)) potentiated seizures induced by both convulsants. Animal Model:Male BKTO mice (25-45 g).Dosage:20 mg/kg (s.c.) and 20 μg (icv in 5 μL).Administration:S.C. and icv.Result:Potentiated seizures induced by both convulsants.
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SynonymsDPPE fumarate
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PathwayGPCR/G Protein
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TargetHistamine Receptor
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RecptorHistamine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1185241-83-1
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Formula Weight399.48
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Molecular FormulaC23H29NO5
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Purity>98% (HPLC)
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SolubilityDMSO:248 mg/mL (620.81 mM; Need ultrasonic)
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SMILESCCN(CC)CCOC1=CC=C(C=C1)CC2=CC=CC=C2.OC(/C=C/C(O)=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Mark Vincent, et al. Tesmilifene may enhance breast cancer chemotherapy by killing a clone of aggressive, multi-drug resistant cells through its action on the p-glycoprotein pump. Med Hypotheses. 2006;66(4):715-31.
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