Metiamide

CAS No. 34839-70-8

Metiamide( SK&F 92058 )

Catalog No. M20781 CAS No. 34839-70-8

Metiamide is a histamine H2-receptor antagonist .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 188 In Stock
5MG 170 In Stock
10MG 282 In Stock
25MG 472 In Stock
50MG 677 In Stock
100MG 923 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Metiamide
  • Note
    Research use only, not for human use.
  • Brief Description
    Metiamide is a histamine H2-receptor antagonist .
  • Description
    Metiamide is a histamine H2-receptor antagonist .
  • In Vitro
    Metiamide (SK&F 92058) is a competitivewith aldehyde substrates and noncompetitive with the Human E3 Aldehyde Dehydrogenase coenzyme, binding to both the free E3 isozyme and the enzyme·coenzyme binary complex with Ki values of 0.92 μM glycolaldehyde as the varied substrate. Data is got as percentage change in GTPase activity induced by metiamide compared with the GTPase activity stimulated by HA (100 μM).
  • In Vivo
    ——
  • Synonyms
    SK&F 92058
  • Pathway
    GPCR/G Protein
  • Target
    Histamine Receptor
  • Recptor
    H2 receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    34839-70-8
  • Formula Weight
    244.38
  • Molecular Formula
    C9H16N4S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:2.4 mg/mL (9.82 mM)
  • SMILES
    CNC(=S)NCCSCc1[nH]cnc1C
  • Chemical Name
    1-methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)thiourea

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Blair E L Grund E R Miller I T et al. Metiamide in the Zollinger-Ellison syndrome[J]. The American Journal of Digestive Diseases 1976 20(12):1123-1130.
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