Metiamide( SK&F 92058 )

Catalog No. M20781 CAS No. 34839-70-8

Metiamide is a histamine H2-receptor antagonist .

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Metiamide
Note

Research use only, not for human use.
Brief Description

Metiamide is a histamine H2-receptor antagonist .
Description

Metiamide is a histamine H2-receptor antagonist .
In Vitro

Metiamide (SK&F 92058) is a competitivewith aldehyde substrates and noncompetitive with the Human E3 Aldehyde Dehydrogenase coenzyme, binding to both the free E3 isozyme and the enzyme·coenzyme binary complex with Ki values of 0.92 μM glycolaldehyde as the varied substrate. Data is got as percentage change in GTPase activity induced by metiamide compared with the GTPase activity stimulated by HA (100 μM).
In Vivo

——
Synonyms

SK&F 92058
Pathway

GPCR/G Protein
Target

Histamine Receptor
Recptor

H2 receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

34839-70-8
Formula Weight

244.38
Molecular Formula

C9H16N4S2
Purity

>98% (HPLC)
Solubility

DMSO:2.4 mg/mL (9.82 mM)
SMILES

CNC(=S)NCCSCc1[nH]cnc1C
Chemical Name

1-methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)thiourea

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Blair E L Grund E R Miller I T et al. Metiamide in the Zollinger-Ellison syndrome[J]. The American Journal of Digestive Diseases 1976 20(12):1123-1130.

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