Dalcotidine

Research use only, not for human use.

Dalcotidine (KU 1257) is a novel histamine H2 receptor antagonist with histamine H9 receptor antagonistic activity and antisecretory effects.

Dalcotidine (KU 1257) is a novel histamine H2 receptor antagonist with histamine H9 receptor antagonistic activity and antisecretory effects.The Ki value for binding to guinea pig cerebral cortex was 0.040 The KB value for antagonism of histamine-induced positive chronotropic responses in the right atrium of isolate guinea pigs was 0.041.Dalcotidine improves the quality of ulcer healing, and may contribute to a reduction in ulcer recurrence and relapse rates.

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GPCR/G Protein

Histamine Receptor

Histamine Receptor

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120958-90-9

319.44

C18H29N3O2

>98% (HPLC)

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C(C1=CC(OCCCNC(NCC)=O)=CC=C1)N2CCCCC2

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(-20℃)

With Ice Pack

≥ 2 years