Dimenhydrinate
CAS No. 523-87-5
Dimenhydrinate( NSC 117855 | NSC-117855 | NSC117855 | Dimenhydrinate | Dramalen | Dramamin )
Catalog No. M14850 CAS No. 523-87-5
Dimenhydrinate is an anti-emetic and anti-histamine commonly available over-the-counter as a motion sickness remedy.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 100MG | 29 | In Stock |
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| 200MG | 41 | In Stock |
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| 500MG | 65 | In Stock |
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| 1G | 91 | In Stock |
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Biological Information
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Product NameDimenhydrinate
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NoteResearch use only, not for human use.
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Brief DescriptionDimenhydrinate is an anti-emetic and anti-histamine commonly available over-the-counter as a motion sickness remedy.
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DescriptionDimenhydrinate is an anti-emetic and anti-histamine commonly available over-the-counter as a motion sickness remedy.
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In Vitro——
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In VivoAnimal Model:Male ICR mice (22-28 g)Dosage:3, 10, and 30 mg/kg Administration:IP; single dose Result:Significantly increased CPP scores (+105.4 s) compared to those of the vehicle-treated control group.
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SynonymsNSC 117855 | NSC-117855 | NSC117855 | Dimenhydrinate | Dramalen | Dramamin
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PathwayGPCR/G Protein
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TargetHistamine Receptor
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RecptorH1 receptor
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number523-87-5
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Formula Weight469.96
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Molecular FormulaC24H28ClN5O3
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESO=C(N1C)N(C)C2=C(NC(Cl)=N2)C1=O.CN(C)CCOC(C3=CC=CC=C3)C4=CC=CC=C4
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Chemical Name8-chloro-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione compound with 2-(benzhydryloxy)-N,N-dimethylethanamine (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Levocetirizine Dihydrochloride (Xyzal Dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Acting as an antihistaminic agent, it specifically targets the histamine H1-receptor.
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Astemizole
Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
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JNJ-5207852 dihydroc...
JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor. JNJ-5207852 is a potent dibasic amine antagonist that binds potently to rat H3 receptors (Ki=1.2?nm), and has good brain penetration. In ex vivo binding studies in mice, the compound had an ED50 of 0.13?mg?kg?1, subcutaneously.
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