ROCK inhibitor-2( —— )

Catalog No. M23320 CAS No. 1127308-52-4

ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
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5MG	160	In Stock
10MG	259	In Stock
25MG	520	In Stock
50MG	750	In Stock
100MG	1035	In Stock
500MG	2061	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

ROCK inhibitor-2
Note

Research use only, not for human use.
Brief Description

ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).
Description

ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

ROCK
Recptor

ROCK1|ROCK2
Research Area

——
Indication

——

Chemical Information

CAS Number

1127308-52-4
Formula Weight

332.4
Molecular Formula

C21H20N2O2
Purity

>98% (HPLC)
Solubility

DMSO:250 mg/mL (752.11 mM; Need ultrasonic)
SMILES

O=C(N[C@@H](C1=CC=CC(OC)=C1)C)C2=CC=C(C3=CC=NC=C3)C=C2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Hobson AD, et al. Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based DrugDesign. J Med Chem. 2018 Dec 27;61(24):11074-11100.

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