H-1152 dihydrochloride( —— )

Catalog No. M34747 CAS No. 871543-07-6

H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	150	In Stock
5MG	138	In Stock
10MG	227	In Stock
25MG	439	In Stock
50MG	677	In Stock
100MG	918	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

H-1152 dihydrochloride
Note

Research use only, not for human use.
Brief Description

H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM.
Description

H-1152 dihydrochloride is a membrane-permeable and selective ROCK inhibitor, with a Ki value of 1.6 nM, and an IC50 value of 12 nM for ROCK2.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

ROCK
Recptor

ROCK
Research Area

——
Indication

——

Chemical Information

CAS Number

871543-07-6
Formula Weight

392.34
Molecular Formula

C16H23Cl2N3O2S
Purity

>98% (HPLC)
Solubility

In Vitro:?H2O : 35.71 mg/mL (91.02 mM; Ultrasonic)DMSO : 10 mg/mL (25.49 mM; Ultrasonic (<60°C)
SMILES

Cl.Cl.C[C@H]1CNCCCN1S(=O)(=O)c1cccc2cncc(C)c12
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Tamura M, et al. Development of specific Rho-kinase inhibitors and their clinical application. Biochim Biophys Acta. 2005 Dec 30;1754(1-2):245-52. Epub 2005 Sep 12.?

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