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Thiazovivin
CAS No. 1226056-71-8
Thiazovivin( Tzv )
Catalog No. M10866 CAS No. 1226056-71-8
Thiazovivin (Tzv) is a novel ROCK inhibitor with IC50 of 0.5 μM, promotes hESC survival after single-cell dissociation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 64 | In Stock |
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| 2MG | 38 | In Stock |
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| 5MG | 59 | In Stock |
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| 10MG | 100 | In Stock |
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| 25MG | 190 | In Stock |
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| 50MG | 314 | In Stock |
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| 100MG | 458 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameThiazovivin
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NoteResearch use only, not for human use.
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Brief DescriptionThiazovivin (Tzv) is a novel ROCK inhibitor with IC50 of 0.5 μM, promotes hESC survival after single-cell dissociation.
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DescriptionThiazovivin (Tzv) is a novel ROCK inhibitor with IC50 of 0.5μM, promotes hESC survival after single-cell dissociation.
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In VitroThiazovivin (GMP) (0.5 ?μM, at 1 day) promotes rapid and efficient reprogramming of mouse tail tip and embryonic fibroblasts into iPSCs.Thiazovivin (GMP) enhances the efficiency in reprograming endometrial adult stromal cells to iPSCs.Thiazovivin (GMP) (2 μM) induces iPSCs and induced neural stem cells (iNSCs) from human urine cells (UCs).Thiazovivin (GMP) (2 μM, for the first 24 h) improves growth rate of hiPSCs.Thiazovivin (GMP) (0.5 μM) together with SB431542 and PD0325901 promotes iPSC reprogramming by regulating cell-cell interactions.
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In Vivo——
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SynonymsTzv
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PathwayCell Cycle/DNA Damage
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TargetROCK
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RecptorROCK
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1226056-71-8
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Formula Weight311.36
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Molecular FormulaC15H13N5OS
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Purity>98% (HPLC)
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SolubilityDMSO: 15 mg/mL (48.17 mM)
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SMILESO=C(C1=CSC(NC2=NC=NC=C2)=N1)NCC3=CC=CC=C3
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Chemical NameN-(phenylmethyl)-2-(4-pyrimidinylamino)-4-thiazolecarboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Yue Xu, et al. PNAS, May 4, 2010 vol. 107 no. 18 8129-8134
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