RBN012759

CAS No. 2360851-29-0

RBN012759( —— )

Catalog No. M22469 CAS No. 2360851-29-0

RBN012759, a potent and selective PARP14 inhibitor, decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 274 In Stock
2MG 149 In Stock
5MG 250 In Stock
10MG 372 In Stock
25MG 645 In Stock
50MG 918 In Stock
100MG 1283 In Stock
200MG 1730 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    RBN012759
  • Note
    Research use only, not for human use.
  • Brief Description
    RBN012759, a potent and selective PARP14 inhibitor, decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants.
  • Description
    RBN012759, a potent and selective PARP14 inhibitor, decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    PARP
  • Recptor
    PARP14
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2360851-29-0
  • Formula Weight
    378.46
  • Molecular Formula
    C19H23FN2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (660.57 mM)
  • SMILES
    O[C@H]1CC[C@@H](CC1)SCc1nc2cc(OCC3CC3)cc(F)c2c(=O)[nH]1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Schenkel L, et, al. A potent and selective PARP14 inhibitor decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants. AACR Annual Meeting 2020.
molnova catalog
related products
  • Senaparib

    Senaparib is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.

  • MK-4827 tosylate

    A highly potent PARP inhibitor with IC50 of 3.8 nM/2.1 nM for PARP1/PARP2.

  • Pamiparib

    Pamiparib (BGB-290, BGB290) is a?highly potent, selective and brain penetrant PARP1/2 inhibitor with potent anti-tumor activity.