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KSQ-4279
CAS No. 2446480-97-1
KSQ-4279( —— )
Catalog No. M35309 CAS No. 2446480-97-1
KSQ-4279 (USP1-IN-1) is an inhibitor of USP1 and PARP, exhibiting anticancer activity. It is utilized in the study of non-small cell lung cancer, osteosarcoma, ovarian, breast, glioblastoma, bladder, uterine, and pancreatic cancers.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 376 | In Stock |
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| 10MG | 560 | In Stock |
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| 25MG | 896 | In Stock |
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| 50MG | 1190 | In Stock |
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| 100MG | 1600 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameKSQ-4279
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NoteResearch use only, not for human use.
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Brief DescriptionKSQ-4279 (USP1-IN-1) is an inhibitor of USP1 and PARP, exhibiting anticancer activity. It is utilized in the study of non-small cell lung cancer, osteosarcoma, ovarian, breast, glioblastoma, bladder, uterine, and pancreatic cancers.
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DescriptionKSQ-4279 (USP1-IN-1) is a potent, first-in-class, and highly selective USP1 inhibitor. KSQ-4279 shows anticancer effects.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetPARP
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RecptorPARP | DUB
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Research Area——
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Indication——
Chemical Information
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CAS Number2446480-97-1
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Formula Weight534.54
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Molecular FormulaC27H25F3N8O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 80 mg/mL (149.66 mM; Ultrasonic )
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SMILESCOc1ncnc(C2CC2)c1-c1ncc2cnn(Cc3ccc(cc3)-c3nc(cn3C(C)C)C(F)(F)F)c2n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Natalie Y L Ngoi, et al. Targeting the DNA damage response beyond poly(ADP-ribose) polymerase inhibitors: novel agents and rational combinations. Curr Opin Oncol. 2022 Sep 1;34(5):559-569.?
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