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Ibrutinib deacryloylpiperidine
CAS No. 330786-24-8
Ibrutinib deacryloylpiperidine( IBT4A,5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine )
Catalog No. M22200 CAS No. 330786-24-8
Ibrutinib deacryloylpiperidine is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 35 | In Stock |
|
| 200MG | 50 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameIbrutinib deacryloylpiperidine
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NoteResearch use only, not for human use.
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Brief DescriptionIbrutinib deacryloylpiperidine is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.
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DescriptionIbrutinib deacryloylpiperidine is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.
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In Vitro——
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In Vivo——
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SynonymsIBT4A,5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine
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PathwayTyrosine Kinase
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TargetBTK
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RecptorBtk
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Research Area——
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Indication——
Chemical Information
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CAS Number330786-24-8
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Formula Weight303.32
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Molecular FormulaC17H13N5O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (82.42 mM)
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SMILESNc3ncnc4nnc(c2ccc(Oc1ccccc1)cc2)c34
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Honigberg LA, et al. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80.
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