Coenzyme A

Research use only, not for human use.

Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.

Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.Covalent binding of Coenzyme A to Peroxiredoxin 5 (Prdx5) results in complete inhibition of its peroxidase activity, which is reversed by reduction with DTT. Many human pathologies, including cancer, diabetes, and neurodegeneration, have been associated with abnormal biosynthesis and homeostasis of CoA and its derivatives.

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Proteasome/Ubiquitin

Endogenous Metabolite

Human Endogenous Metabolite

Cardiovascular system

Hyperlipoproteinemia

85-61-0

767.53

C21H36N7O16P3S

>98% (HPLC)

In Vitro:?H2O : 125 mg/mL (162.86 mM)

CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCS

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(-20℃)

With Ice Pack

≥ 2 years