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Istaroxime hydrochloride
CAS No. 374559-48-5
Istaroxime hydrochloride( —— )
Catalog No. M33386 CAS No. 374559-48-5
Istaroxime hydrochloride (PST2744 hydrochloride) is a Na+/K+-ATPase inhibitor and sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA 2) activator, a novel positive inotropic compound that can be used to study acute heart failure.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 218 | Get Quote |
|
| 10MG | 357 | Get Quote |
|
| 50MG | 726 | Get Quote |
|
| 100MG | 1062 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameIstaroxime hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionIstaroxime hydrochloride (PST2744 hydrochloride) is a Na+/K+-ATPase inhibitor and sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA 2) activator, a novel positive inotropic compound that can be used to study acute heart failure.
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DescriptionIstaroxime hydrochloride is a Na+/K+-ATPase inhibitor (IC50=0.11 μM) and a sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA 2) activator.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetATPase
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RecptorATPase
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Research Area——
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Indication——
Chemical Information
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CAS Number374559-48-5
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Formula Weight396.95
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Molecular FormulaC21H33ClN2O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 45 mg/mL (113.36 mM ) H2O : 25 mg/mL (62.98 mM; Ultrasonic)
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SMILESC[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)C(=O)CC4)[H])(CC(=O)[C@]1(CC(=NOCCN)CC2)[H])[H])[H].Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gobbini M, et al. Novel analogues of istaroxime, a potent inhibitor of Na+,K+-ATPase: synthesis and structure-activity relationship. J Med Chem. 2008 Aug 14;51(15):4601-8.?
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