Wilforine

Research use only, not for human use.

Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants and is effective in treating idiopathic pulmonary fibrosis.

Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect which might be mediated by down-regulation of the expression of inflammatory factors TNF-α IL-6 and NO. It also has insecticidal activity by inhibiting the Na+-K+-ATPase in the central nervous system.

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Endocrinology/Hormones

ATPase

(NaK)-ATPase

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11088-09-8

867.85

C43H49NO18

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (57.61 mM)

C[C@@H](CCc(nccc1)c1C(OC[C@@](C)([C@@H]([C@H]1OC(C)=O)[C@H]([C@H]2OC(C)=O)OC(C)=O)O[C@@]1([C@](C)([C@H]([C@@H]1OC(c3ccccc3)=O)O3)O)[C@]2(COC(C)=O)[C@H]1OC(C)=O)=O)C3=O

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(-20℃)

With Ice Pack

≥ 2 years