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S1R agonist 2
CAS No. 150085-21-5
S1R agonist 2( —— )
Catalog No. M36422 CAS No. 150085-21-5
S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 32 | In Stock |
|
| 5MG | 53 | In Stock |
|
| 10MG | 85 | In Stock |
|
| 25MG | 163 | In Stock |
|
| 50MG | 243 | In Stock |
|
| 100MG | 359 | In Stock |
|
| 200MG | 507 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameS1R agonist 2
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NoteResearch use only, not for human use.
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Brief DescriptionS1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.
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DescriptionS1R agonist 2 (Compound 8b) is a selective S1R agonist with Kis of 1.1 nM and 88 nM for S1R and S2R, respectively. S1R agonist 2 exhibits neuroprotection against ROS and NMDA-induced neurotoxicity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetSigma receptor
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RecptorSigma receptor | ROS | NMDAR
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Research Area——
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Indication——
Chemical Information
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CAS Number150085-21-5
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Formula Weight309.45
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Molecular FormulaC21H27NO
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Purity>98% (HPLC)
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Solubility——
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SMILESC(C1CCN(CCCOC2=CC=CC=C2)CC1)C3=CC=CC=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Linciano P, et al. Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents. Eur J Med Chem. 2023 Mar 5;249:115163.?
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