Cart
sales@molnova.com
4-Phenoxybenzylamine
CAS No. 107622-80-0
4-Phenoxybenzylamine( —— )
Catalog No. M20512 CAS No. 107622-80-0
4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 43 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name4-Phenoxybenzylamine
-
NoteResearch use only, not for human use.
-
Brief Description4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .
-
Description4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .
-
In VitroA highly conserved novel binding site located at the interface between the protease and helicase domains of the Hepatitis C Virus (HCV) NS3 protein is identified. 4-Phenoxybenzylamine binding at this allosteric site inhibits the function of the NS3 protein by stabilizing an inactive conformation and thus represents a new class of direct acting antiviral agents.
-
In Vivo——
-
Synonyms——
-
PathwayMicrobiology/Virology
-
TargetHCV
-
RecptorHCV NS3/4A
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number107622-80-0
-
Formula Weight199.25
-
Molecular FormulaC13H13NO
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 12.5 mg/mL (62.74 mM)
-
SMILESNCc1ccc(Oc2ccccc2)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Saalau-Bethell S M Woodhead A J Chessari G et al. Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function[J]. Nature Chemical Biology 2012 8(11):2354.
molnova catalog
related products
-
Ciluprevir
Ciluprevir (BILN2061) is a potent HCV NS3/4A protease inhibitor with Ki of 0.66 and 0.30 nM for NS3-NS4A protease of HCV 1b and HCV 1a, respectively.
-
Paritaprevir
Paritaprevir (ABT-450, Veruprevir) is a potent HCV NS3/4A protease inhibitor with EC50 of 1 and 0.21 nM for HCV GT 1a and 1b, respectively.
-
Deleobuvir
Deleobuvir (BI-207127, BI207127) is a potent, selective HCV NS5B polymerase inhibitor with IC50 of 50 nM against GT-1 HCV polymerase activity.
