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Uprifosbuvir
CAS No. 1496551-77-9
Uprifosbuvir( MK3682 | IDX 21437 )
Catalog No. M12075 CAS No. 1496551-77-9
A novel uridine nucleotide analog HCV NS5B polymerase inhibitor for treatment of HCV infection combined with Grazoprevir and Ruzasvir.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 188 | In Stock |
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| 10MG | 312 | In Stock |
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| 25MG | 635 | In Stock |
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| 50MG | 995 | In Stock |
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| 100MG | 1609 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameUprifosbuvir
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NoteResearch use only, not for human use.
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Brief DescriptionA novel uridine nucleotide analog HCV NS5B polymerase inhibitor for treatment of HCV infection combined with Grazoprevir and Ruzasvir.
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DescriptionA novel uridine nucleotide analog HCV NS5B polymerase inhibitor for treatment of HCV infection combined with Grazoprevir and Ruzasvir.HCV Infection Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsMK3682 | IDX 21437
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PathwayMicrobiology/Virology
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TargetHCV
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RecptorHCV
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number1496551-77-9
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Formula Weight545.91
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Molecular FormulaC22H29ClN3O9P
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (457.95 mM)
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SMILESC[C@@H](C(OC(C)C)=O)N[P@@](OC1=CC=CC=C1)(OC[C@H]2O[C@@H](N(C(N3)=O)C=CC3=O)[C@](C)(Cl)[C@@H]2O)=O
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Chemical NamePropan-2-yl (2R)-2-{[(R)-({(2R,3R,4R,5R)-4-chloro-5-[2,4-dioxo-3,4dihydropyrimidin-1(2H)-yl]-3-hydroxy-4-methyloxolan-2yl}methoxy)(phenoxy)phosphoryl]amino}propanoate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wyles D, et al. Hepatology. 2017 Jul 7. doi: 10.1002/hep.29358.
2. Lawitz E, et al. Lancet Gastroenterol Hepatol. 2017 Aug 9. pii: S2468-1253(17)30163-2.
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