Sclareolide
CAS No. 564-20-5
Sclareolide( Sclareolide | Norambreinolide )
Catalog No. M18818 CAS No. 564-20-5
Sclareolide is a sesquiterpene lactone natural product derived from various plant sources including Salvia yosgadensis, Salvia sclarea, and cigar tobacco. It is a close analog of Sclareol, a plant antifungal compound.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
|
| 200MG | 29 | In Stock |
|
| 500MG | 45 | In Stock |
|
| 1G | 63 | In Stock |
|
Biological Information
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Product NameSclareolide
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NoteResearch use only, not for human use.
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Brief DescriptionSclareolide is a sesquiterpene lactone natural product derived from various plant sources including Salvia yosgadensis, Salvia sclarea, and cigar tobacco. It is a close analog of Sclareol, a plant antifungal compound.
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DescriptionSclareolide is a sesquiterpene lactone natural product derived from various plant sources. It is a close analog of sclareol, a plant antifungal compound.
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In VitroSclareolide has a good antibacterial activity against Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27950,Escherichia coli ATCC 25922 and Enterococcus faecalis ATCC 29212.
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In Vivo——
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SynonymsSclareolide | Norambreinolide
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PathwayImmunology/Inflammation
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TargetIκB kinase (IKK)
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number564-20-5
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Formula Weight250.38
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Molecular FormulaC16H26O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (399.39 mM)
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SMILESC[C@]12CCCC([C@@H]1CC[C@@]1([C@@H]2CC(=O)O1)C)(C)C
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Chemical Name(3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyldecahydronaphtho[2,1-b]furan-2(1H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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IKK2-IN-4
IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.
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IMD-0354
A potent, selective IKKβ inhibitor that inhibits NF-κB activity both in vitro and in vivo.
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BOT-64
BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathiole compoundBOT-64 inhibits IKKbeta-mediated IkappaBalpha phosphorylation in LPS-activated macrophages, resulting in sequential prevention of downstream events, including proteolytic degradation of IkappaBalpha, DNA binding ability, and transcriptional activity of NF-kappaB.?
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