AZD3264( AZD-3264 | AZD 3264 )

Catalog No. M12315 CAS No. 1609281-86-8

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

AZD3264
Note

Research use only, not for human use.
Brief Description

A novel IkB-kinase IKK2 inhibitor for treatment of inflammatory conditions such as asthma, chronic pulmonary obstructive disorder (COPD) and rheumatoid arthritis.
Description

A novel IkB-kinase IKK2 inhibitor for treatment of inflammatory conditions such as asthma, chronic pulmonary obstructive disorder (COPD) and rheumatoid arthritis.
In Vitro

——
In Vivo

AZD3264 is a selective IkB-kinase IKK2 inhibitor, which is currently in preclinical development for the potential treatment of chronic pulmonary obstructive disorder (COPD) and asthma.
Synonyms

AZD-3264 | AZD 3264
Pathway

Immunology/Inflammation
Target

IκB kinase (IKK)
Recptor

IKK2
Research Area

Inflammation/Immunology
Indication

——

CAS Number

1609281-86-8
Formula Weight

441.5034
Molecular Formula

C21H23N5O4S
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 48 mg/mL
SMILES

O=C(C1=C(NC(N)=O)SC(C2=CC=C(C3=C(C)ON=C3C)C=C2O[C@@H]4CNCC4)=C1)N
Chemical Name

3-Thiophenecarboxamide, 2-[(aminocarbonyl)amino]-5-[4-(3,5-dimethyl-4-isoxazolyl)-2-[(3S)-3-pyrrolidinyloxy]phenyl]-