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Triprolidine hydrochloride

CAS No. 6138-79-0

Triprolidine hydrochloride( —— )

Catalog No. M15313 CAS No. 6138-79-0

Histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Triprolidine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria.
  • Description
    Histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of COUGH and COLD medicines. It may cause drowsiness.(In Vivo):Triprolidine hydrochloride monohydrate (292.81-1467.20 μg/kg; intrathecal injection) produces a dose-dependent effect of spinal motor and sensory block in rats.
  • In Vitro
    ——
  • In Vivo
    Triprolidine hydrochloride monohydrate (292.81-1467.20 μg/kg; intrathecal injection) produces a dose-dependent effect of spinal motor and sensory block in rats. Animal Model:Male Sprague-Dawley rat (300-350 g)Dosage:292.81 μg/kg, 488.02 μg/kg, 733.60μg/kg, 1098.83 μg/kg, 1467.20 μg/kg Administration:Intrathecal injection Result:Elicited a dose-dependent spinal block.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Histamine Receptor
  • Recptor
    H1 receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6138-79-0
  • Formula Weight
    314.85
  • Molecular Formula
    C19H23ClN2
  • Purity
    >98% (HPLC)
  • Solubility
    Soluble in Water
  • SMILES
    CC1=CC=C(C=C1)/C(=C\CN2CCCC2)/C3=CC=CC=N3.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hansen EB Jr, et al. J Pharm Sci. 1988 Mar;77(3):259-64.
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