Astemizole( NSC 329963 )

Catalog No. M15631 CAS No. 68844-77-9

COA

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Product Name

Astemizole
Note

Research use only, not for human use.
Brief Description

Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
Description

Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
In Vitro

——
In Vivo

——
Synonyms

NSC 329963
Pathway

GPCR/G Protein
Target

Histamine Receptor
Recptor

H1 receptor| Potassium Channel
Research Area

Inflammation/Immunology
Indication

——

CAS Number

68844-77-9
Formula Weight

458.58
Molecular Formula

C28H31FN4O
Purity

>98% (HPLC)
Solubility

Water: 432 mg/L
SMILES

COC1=CC=C(C=C1)CCN2CCC(CC2)NC3=NC4=CC=CC=C4N3CC5=CC=C(C=C5)F
Chemical Name

1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl]benzimidazol-2-amine

1.Salata JJ, et al. Circ Res. 1995 Jan;76(1):110-9.

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