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Camostat mesilate

CAS No. 59721-29-8

Camostat mesilate( Foipan | FOY 305 )

Catalog No. M15218 CAS No. 59721-29-8

Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	46	In Stock
10MG	41	In Stock
25MG	63	In Stock
50MG	83	In Stock
100MG	116	In Stock
200MG	172	In Stock
500MG	291	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Camostat mesilate
Note

Research use only, not for human use.
Brief Description

Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.
Description

Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.
In Vitro

——
In Vivo

Animal Model:6-8 week old female BALB/c mice (lethal SARS-CoV infection model)Dosage:30 mg/kg Administration:P.o.; twice a day for 9 days Result:Effective in protecting mice against death due to a lethal infection by SARS-CoV, with a survival rate of ～60%.
Synonyms

Foipan | FOY 305
Pathway

Membrane Transporter/Ion Channel
Target

Sodium Channel
Recptor

epithelial sodium channel (ENaC)
Research Area

Metabolic Disease
Indication

——

Chemical Information

CAS Number

59721-29-8
Formula Weight

494.52
Molecular Formula

C21H26N4O8S
Purity

>98% (HPLC)
Solubility

Water: 10 mg/mL (20.22 mM); DMSO: 99 mg/mL (200.19 mM)
SMILES

CS(O)(=O)=O.CN(C)C(=O)COC(=O)CC1=CC=C(OC(=O)C2=CC=C(C=C2)N=C(N)N)C=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Coote K, et al. J Pharmacol Exp Ther, 2009, 329(2), 764-774.

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