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Camostat mesilate
CAS No. 59721-29-8
Camostat mesilate( Foipan | FOY 305 )
Catalog No. M15218 CAS No. 59721-29-8
Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
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| 10MG | 41 | In Stock |
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| 25MG | 63 | In Stock |
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| 50MG | 83 | In Stock |
|
| 100MG | 116 | In Stock |
|
| 200MG | 172 | In Stock |
|
| 500MG | 291 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCamostat mesilate
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NoteResearch use only, not for human use.
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Brief DescriptionCamostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.
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DescriptionCamostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.
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In Vitro——
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In VivoAnimal Model:6-8 week old female BALB/c mice (lethal SARS-CoV infection model)Dosage:30 mg/kg Administration:P.o.; twice a day for 9 days Result:Effective in protecting mice against death due to a lethal infection by SARS-CoV, with a survival rate of ～60%.
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SynonymsFoipan | FOY 305
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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Recptorepithelial sodium channel (ENaC)
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Research AreaMetabolic Disease
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Indication——
Chemical Information
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CAS Number59721-29-8
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Formula Weight494.52
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Molecular FormulaC21H26N4O8S
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Purity>98% (HPLC)
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SolubilityWater: 10 mg/mL (20.22 mM); DMSO: 99 mg/mL (200.19 mM)
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SMILESCS(O)(=O)=O.CN(C)C(=O)COC(=O)CC1=CC=C(OC(=O)C2=CC=C(C=C2)N=C(N)N)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Coote K, et al. J Pharmacol Exp Ther, 2009, 329(2), 764-774.
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