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Tocainide

CAS No. 41708-72-9

Tocainide( —— )

Catalog No. M24378 CAS No. 41708-72-9

Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Tocainide
  • Note
    Research use only, not for human use.
  • Brief Description
    Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus.
  • Description
    Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus.(In Vivo):Tocainide (100 mg/kg) effectively suppresses ventricular ectopic activity in unanesthetized dogs with coronary occlusion. Termination of tocainide infusion in both digitalis toxicity and coronary occlusion models results in prompt return of ventricular ectopic activity.
  • In Vitro
    ——
  • In Vivo
    Tocainide (100 mg/kg) effectively suppresses ventricular ectopic activity in unanesthetized dogs with coronary occlusion. Termination of tocainide infusion in both digitalis toxicity and coronary occlusion models results in prompt return of ventricular ectopic activity.
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    sodium channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    41708-72-9
  • Formula Weight
    192.13
  • Molecular Formula
    C11H16N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CC(N)C(NC1=C(C)C=CC=C1C)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Alpert JS, et al. Chemistry, pharmacology, antiarrhythmic efficacy and adverse effects of tocainide hydrochloride, an orally active structural analog of lidocaine. Pharmacotherapy. 1983 Nov-Dec;3(6):316-23.
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