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Flecainide

CAS No. 54143-55-4

Flecainide( Flecainide, Flecainida, Flecainidum, Tambocor, Apocard )

Catalog No. M14935 CAS No. 54143-55-4

A class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias, works by blocking the Nav1.5 sodium channel in the heart.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 42 In Stock
5MG 38 In Stock
10MG 61 In Stock
25MG 113 In Stock
50MG 183 In Stock
100MG 276 In Stock
200MG 347 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Flecainide
  • Note
    Research use only, not for human use.
  • Brief Description
    A class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias, works by blocking the Nav1.5 sodium channel in the heart.
  • Description
    A class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias, works by blocking the Nav1.5 sodium channel in the heart, slowing the upstroke of the cardiac action potential; also inhibits ryanodine receptor 2 (RyR2), reduces calcium sparks and thus arrhythmogenic calcium waves in the heart.Heart Arrhythmia Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Flecainide, Flecainida, Flecainidum, Tambocor, Apocard
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    Sodium Channel
  • Research Area
    Cardiovascular Disease
  • Indication
    Heart Arrhythmia

Chemical Information

  • CAS Number
    54143-55-4
  • Formula Weight
    414.343
  • Molecular Formula
    C17H20F6N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (241.35 mM)
  • SMILES
    O=C(NCC1NCCCC1)C2=CC(OCC(F)(F)F)=CC=C2OCC(F)(F)F
  • Chemical Name
    N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hilliard FA, et al. J Mol Cell Cardiol. 2010 Feb;48(2):293-301. 2. Salvage SC, et al. Acta Physiol (Oxf). 2015 Jul;214(3):361-75. 3. Salvage SC, et al. Br J Pharmacol. 2017 Apr 3. doi: 10.1111/bph.13807.
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