Vapendavir

CAS No. 439085-51-5

Vapendavir( BTA798 | BTA-798 )

Catalog No. M14491 CAS No. 439085-51-5

Vapendavir (BTA798) is a novel potent enteroviral capsid binder, inhibits EV71 replication of all isolates with mean EC50 of 0.7 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Vapendavir
  • Note
    Research use only, not for human use.
  • Brief Description
    Vapendavir (BTA798) is a novel potent enteroviral capsid binder, inhibits EV71 replication of all isolates with mean EC50 of 0.7 uM.
  • Description
    Vapendavir (BTA798) is a novel potent enteroviral capsid binder, inhibits EV71 replication of all isolates with mean EC50 of 0.7 uM; efficiently inhibits the in vitro replication of 21 EV71 strains/isolates that are representative of the different genogroups A, B, and C; Vapendavir (BTA798) is currently under clinical study for the treatment of rhinovirus infections.Rhinovirus Infection Phase 2 Clinical.
  • In Vitro
    Vapendavir (BTA798) efficiently inhibit the in vitro replication of 21 EV71 strains/isolates that are representative of the different genogroups A, B, and C.
  • In Vivo
    ——
  • Synonyms
    BTA798 | BTA-798
  • Pathway
    Microbiology/Virology
  • Target
    Enterovirus
  • Recptor
    Enterovirus
  • Research Area
    Infection
  • Indication
    Rhinovirus Infection

Chemical Information

  • CAS Number
    439085-51-5
  • Formula Weight
    382.464
  • Molecular Formula
    C21H26N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=NN=C(N2CCC(CCOC3=CC=C4C(OCC)=NOC4=C3)CC2)C=C1
  • Chemical Name
    3-ethoxy-6-[2-[1-(6-methylpyridazin-3-yl)piperidin-4-yl]ethoxy]-1,2-benzoxazole

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tijsma A, et al. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2. 2. Sun L, et al. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5.
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