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NBD-556
CAS No. 333353-44-9
NBD-556( NBD 556 | NBD556 )
Catalog No. M14123 CAS No. 333353-44-9
A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 30 | In Stock |
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| 5MG | 28 | In Stock |
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| 10MG | 46 | In Stock |
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| 25MG | 87 | In Stock |
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| 50MG | 133 | In Stock |
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| 100MG | 200 | In Stock |
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| 200MG | 295 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNBD-556
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NoteResearch use only, not for human use.
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Brief DescriptionA potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction.
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DescriptionA potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; inhibits the fusion between HIV-1NL4-3-luc pseudotyped virus expressing HIV-1HXB2 (X4-tropic) envelope and U87-T4-CXCR4 cells with IC50 of 20 uM; inhibits the laboratory-adapted HIV-1 strains IIIB, MN, and V32 with IC50 of 5-16 uM.HIV Infection Preclinical.
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In VitroNBD-556 (1-100 μM) inhibits HIV-1 envelope-mediated virus-cell and cell-cell fusion.NBD-556 inhibits the infection of MT-2 cells by laboratory-adapted HIV-1 IIIB, MN, and V32 strains, with IC50s of 6.5, 15.9, and 5.3 μM, respectively.NBD-556 (1-100 μM) inhibits the CD4-dependent virus in a dose-dependent manner with an IC50 of 22.6 μM.
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In Vivo——
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SynonymsNBD 556 | NBD556
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research AreaInfection
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IndicationHIV Infection
Chemical Information
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CAS Number333353-44-9
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Formula Weight337.8444
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Molecular FormulaC17H24ClN3O2
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(NC1CC(C)(C)NC(C)(C)C1)C(NC2=CC=C(Cl)C=C2)=O
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Chemical NameEthanediamide, N1-(4-chlorophenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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HIV gag peptide 197-...
HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETI).
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Helichrysetin
Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.Searching for anti-HIV-1 protease (PR) inhibitors of Thai medicinal plants led to the isolation of a new cyclohexenyl chalcone named panduratin C and chalcone derivatives (2-6) from the methanol extract of Boesenbergia pandurata rhizomes.
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(2RS)-FPMPA
(2RS)-FPMPA（FPMPA） has antiviral activity with an IC50 value of 1.85 μM measured in human MT12 cells infected with SHIV (DH4R).
