SodiumCholate( Cholic acid sodium )

Catalog No. M21208 CAS No. 361-09-1

SodiumCholate exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

SodiumCholate
Note

Research use only, not for human use.
Brief Description

SodiumCholate exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity.
Description

SodiumCholate exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity.
In Vitro

——
In Vivo

Animal Model:Tg-CYP2D6 adult male mice (8 weeks of age and weighing 20–25 g).Dosage:1% (w/w) Cholic acid-supplemented diet Administration:Oral, 14 days Result:Decreases SHP expression and increased CYP2D6 activity.
Synonyms

Cholic acid sodium
Pathway

Microbiology/Virology
Target

HIV
Recptor

HIV
Research Area

——
Indication

——

Chemical Information

CAS Number

361-09-1
Formula Weight

430.6
Molecular Formula

C24H39NaO5
Purity

>98% (HPLC)
Solubility

DMSO:86 mg/mL (199.74 mM)
SMILES

C[C@H](CCC(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C.[Na+]
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Psychoyos A Creatsas G Hassan E et al. Spermicidal and antiviral properties of cholic acid: contraceptive efficacy of a new vaginal sponge (ProtectaidR) containing sodium cholate[J]. Human Reproduction(6):6.

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