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RU1968
CAS No. 171336-24-6
RU1968( RU 1968 | RU-1968 )
Catalog No. M12611 CAS No. 171336-24-6
RU1968 is a potent, cross-species sperm-specific Ca2+ channel CatSper inhibitor that is selective for CatSper over Slo3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | In Stock |
|
| 50MG | 1782 | In Stock |
|
| 100MG | 2250 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRU1968
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NoteResearch use only, not for human use.
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Brief DescriptionRU1968 is a potent, cross-species sperm-specific Ca2+ channel CatSper inhibitor that is selective for CatSper over Slo3.
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DescriptionRU1968 is a potent, cross-species sperm-specific Ca2+ channel CatSper inhibitor that is selective for CatSper over Slo3; suppresses progesterone- and prostaglandin-induced Ca2+ signals in human sperm (IC50=4 and 3.8 uM), potently abolishes CatSper-mediated Ca2+ signals in mouse, human, and sea urchin sperm.
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In Vitro——
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In Vivo——
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SynonymsRU 1968 | RU-1968
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number171336-24-6
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Formula Weight370.581
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Molecular FormulaC24H38N2O
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Purity>98% (HPLC)
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Solubility——
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SMILESOC1=CC=C2[C@@]3([H])CC[C@]4(C)[C@@H](C(NCCN(C)C)C)CC[C@@]4([H])[C@]3([H])CCC2=C1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
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Chemical Name(8R,9R,13R,14R,17R)-17-((R)-1-((2-(dimethylamino)ethyl)amino)ethyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-ol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Rennhack A, et al. Br J Pharmacol. 2018 May 3. doi: 10.1111/bph.14355.
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