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NSC654259
CAS No. 150068-95-4
NSC654259( NSC-654259 | NSC 654259 )
Catalog No. M12087 CAS No. 150068-95-4
A novel small molecule Wnt signaling inhibitor that targets the cysteine-rich domain of Frizzled.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameNSC654259
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NoteResearch use only, not for human use.
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Brief DescriptionA novel small molecule Wnt signaling inhibitor that targets the cysteine-rich domain of Frizzled.
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DescriptionA novel small molecule Wnt signaling inhibitor that targets the cysteine-rich domain of Frizzled, specifically binds to the Wnt binding site on the Frizzled8 cysteine-rich domain with Kd of 2.9 uM, IC50 of 5.7 uM.
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In Vitro——
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In Vivo——
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SynonymsNSC-654259 | NSC 654259
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PathwayWnt/Notch/Hedgehog
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TargetFrizzled
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RecptorFrizzled
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Research Area——
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Indication——
Chemical Information
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CAS Number150068-95-4
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Formula Weight535.783
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Molecular FormulaC21H20BrClN6O4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name2-[(2-aminoacetyl)amino]-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-methylphenyl]carbamoyl]benzamide;hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lee HJ, et al. J Biol Chem. 2015 Dec 18;290(51):30596-606.
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