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MRL-1237
CAS No. 276704-21-3
MRL-1237( MRL1237 )
Catalog No. M13847 CAS No. 276704-21-3
MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameMRL-1237
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NoteResearch use only, not for human use.
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Brief DescriptionMRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein.
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DescriptionMRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein; inhibits poliovirus-specific RNA synthesis in HeLa cells infected with a wild strain but not with an F164Y mutant.
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In Vitro——
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In Vivo——
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SynonymsMRL1237
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PathwayMicrobiology/Virology
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TargetEnterovirus
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RecptorEnterovirus
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Research Area——
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Indication——
Chemical Information
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CAS Number276704-21-3
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Formula Weight354.813
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Molecular FormulaC19H16ClFN4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name1-((1-(4-fluorophenyl)-1H-benzo[d]imidazol-2-yl)methyl)pyridin-4(1H)-imine hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Shimizu H, et al. J Virol. 2000 May;74(9):4146-54.
2. De Palma AM, et al. J Virol. 2008 May;82(10):4720-30.
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