KUNG29

CAS No. 1887032-92-9

KUNG29( KUNG-29 | KUNG 29 )

Catalog No. M12952 CAS No. 1887032-92-9

A potent, selective Grp94 inhibitor with Kd of 0.2 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    KUNG29
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective Grp94 inhibitor with Kd of 0.2 uM.
  • Description
    A potent, selective Grp94 inhibitor with Kd of 0.2 uM; displays 40-fold selecticity over Hsp90α; induces the degradation of integrin α2 in MDA-MB-231 cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    KUNG-29 | KUNG 29
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    HSP
  • Recptor
    HSP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1887032-92-9
  • Formula Weight
    430.89
  • Molecular Formula
    C22H23ClN2O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(OC)C1=C(O)C=C(O)C(Cl)=C1CCC2=NC=CN2CC3=CC=CC=C3OCC
  • Chemical Name
    Methyl 3-Chloro-2-(2-(1-(2-ethoxybenzyl)-1H-imidazol-2-yl)-ethyl)-4,6-dihydroxybenzoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Crowley VM, et al. J Med Chem. 2016 Apr 14;59(7):3471-88.
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