IU1-248
CAS No.
IU1-248 ( USP14 inhibitor IU1-248 )
Catalog No. M17003 CAS No.
IU1-248 (USP14 inhibitor IU1-248) is a potent, selective USP14 inhibitor with IC50 of 0.83 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
Biological Information
-
Product NameIU1-248
-
NoteResearch use only, not for human use.
-
Brief DescriptionIU1-248 (USP14 inhibitor IU1-248) is a potent, selective USP14 inhibitor with IC50 of 0.83 uM.
-
DescriptionIU1-248 (USP14 inhibitor IU1-248) is a potent, selective USP14 inhibitor with IC50 of 0.83 uM, IU1-248 is an IU1 derivative that is 10-fold more potent than IU1; exhibits 25-fold selectivity over USP5 (IsoT).
-
SynonymsUSP14 inhibitor IU1-248
-
PathwayProteasome/Ubiquitin
-
TargetDUB
-
RecptorDUB
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number--
-
Formula Weight337.42
-
Molecular FormulaC20H23N3O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name4-(3-(2-(4-hydroxypiperidin-1-yl)acetyl)-2,5-dimethyl-1H-pyrrol-1-yl)benzonitrile
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Wang Y, et al. Cell Res. 2018 Sep 25. doi: 10.1038/s41422-018-0091-x.
molnova catalog
related products
-
ML364
A potent, selective, reversible deubiquitinase USP2 inhibitor with IC50 of 1.1 uM in biochemical assay.
-
USP8-IN-22c
A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM.
-
XL177A
XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34?nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.