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USP8-IN-22c
CAS No. 924296-17-3
USP8-IN-22c( —— )
Catalog No. M16621 CAS No. 924296-17-3
A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 178 | Get Quote |
|
| 5MG | 309 | Get Quote |
|
| 10MG | 441 | Get Quote |
|
| 25MG | 705 | Get Quote |
|
| 50MG | 981 | Get Quote |
|
| 100MG | 1332 | Get Quote |
|
| 500MG | 2655 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameUSP8-IN-22c
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM.
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DescriptionA potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM; shows no inhibitory activity for USP7, USP5, SENP1, Uch-L3, and caspase 3 (IC50>100 uM), and displays partial activity against Uch-L3; inhibits the viability of HCT116 colon and PC-3 prostate cancer cell lines with IC50 values in the 0.5-1.5 uM range.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetDUB
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RecptorDUB
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number924296-17-3
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Formula Weight287.2756
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Molecular FormulaC16H9N5O
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Purity>98% (HPLC)
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SolubilityDMSO: 20.1 mg/mL
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SMILESC=CCON=C1C2=CC=CC=C2C3=NC(=C(N=C31)C#N)C#N
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Chemical Name9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 9-[(2-propen-1-yloxy)imino]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Colombo M, et al. ChemMedChem. 2010 Apr 6;5(4):552-8.
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