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XL177A
CAS No. 2417089-74-6
XL177A ( —— )
Catalog No. M24114 CAS No. 2417089-74-6
XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34?nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 177 | In Stock |
|
| 10MG | 282 | In Stock |
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| 25MG | 480 | In Stock |
|
| 50MG | 691 | In Stock |
|
| 100MG | 972 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameXL177A
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NoteResearch use only, not for human use.
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Brief DescriptionXL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34?nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.
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DescriptionXL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34?nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetDUB
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RecptorUSP7
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Research Area——
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Indication——
Chemical Information
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CAS Number2417089-74-6
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Formula Weight861.5
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Molecular FormulaC48H57ClN8O5
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC1=CC(N=CN2CC3(O)CCN(C([C@H](CC4=CC=CC=C4)CCCNC(C5=CC(N=C(CCCC6)C6=C7Cl)=C7C=C5)=O)=O)CC3)=C(C=C1)C2=O)CCN8CCN(C)CC8
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Nathan J Schauer, et al. Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism. Sci Rep.2020 Mar 24;10(1):5324.
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