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GSK126
CAS No. 1346574-57-9
GSK126 ( GSK2816126; GSK-2816126; GSK 2816126 )
Catalog No. M11403 CAS No. 1346574-57-9
GSK126 is a potent, highly selective EZH2 methyltransferase inhibitor with IC50 of 9.9 nM.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 33 | In Stock |
|
| 5MG | 53 | In Stock |
|
| 10MG | 81 | In Stock |
|
| 25MG | 139 | In Stock |
|
| 50MG | 215 | In Stock |
|
| 100MG | 331 | In Stock |
|
| 200MG | 431 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGSK126
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NoteResearch use only, not for human use.
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Brief DescriptionGSK126 is a potent, highly selective EZH2 methyltransferase inhibitor with IC50 of 9.9 nM.
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DescriptionGSK126 is a potent, highly selective EZH2 methyltransferase inhibitor with IC50 of 9.9 nM, >1000-fold selective for EZH2 over 20 other human methyltransferases.
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SynonymsGSK2816126; GSK-2816126; GSK 2816126
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PathwayChromatin/Epigenetic
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TargetHMTase
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RecptorEZH2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1346574-57-9
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Formula Weight526.67
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Molecular FormulaC31H38N6O2
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Purity>98%(HPLC)
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SolubilityDMSO: 3 mg/mL warmed (5.69 mM)
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SMILESO=C(C1=CC(C2=CC=C(N3CCNCC3)N=C2)=CC4=C1C(C)=CN4[C@@H](C)CC)NCC5=C(C)C=C(C)NC5=O
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Chemical Name(S)-1-(sec-butyl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.McCabe MT, et al. Nature. 2012, 492(7427), 108-112.
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