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EPZ-030456
CAS No. 1808011-23-5
EPZ-030456 ( EPZ 030456;EPZ030456 )
Catalog No. M12764 CAS No. 1808011-23-5
EPZ-030456 (EPZ030456) is a potent, selective SMYD3 inhibitor with biochem IC50 of 4 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1233 | Get Quote |
|
| 50MG | 2502 | Get Quote |
|
| 100MG | 3330 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameEPZ-030456
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NoteResearch use only, not for human use.
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Brief DescriptionEPZ-030456 (EPZ030456) is a potent, selective SMYD3 inhibitor with biochem IC50 of 4 nM.
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DescriptionEPZ-030456 (EPZ030456) is a potent, selective SMYD3 inhibitor with biochem IC50 of 4 nM; displays noncompetitive inhibition with respect to SAM and MEKK2 with Ki of 1.2 and 1.1 nM, respectively; has cellular potency (IC50=48 nM) suitable to probe the in vitro biology of SMYD3 inhibition.
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SynonymsEPZ 030456;EPZ030456
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PathwayChromatin/Epigenetic
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TargetHMTase
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RecptorHMTase
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Research Area——
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Indication——
Chemical Information
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CAS Number1808011-23-5
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Formula Weight572.12
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Molecular FormulaC28H34ClN5O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=CC2=C(NC(C2)=O)C=C1Cl)N[C@H]3C[C@@](N4S(=O)(N5CCC(NCC6=CC=CC=C6)CC5)=O)([H])CC[C@@]4([H])C3
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Chemical NameN-((1R,3r,5S)-8-((4-(benzylamino)piperidin-1-yl)sulfonyl)-8-azabicyclo[3.2.1]octan-3-yl)-6-chloro-2-oxoindoline-5-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mitchell LH, et al. ACS Med Chem Lett. 2015 Aug 27;7(2):134-8.
molnova catalog
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