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Fenbufen

CAS No. 36330-85-5

Fenbufen( Fenbufen | Cinopal | Lederfen | CL-82204 | CL 82204 | CL82204 )

Catalog No. M14247 CAS No. 36330-85-5

Fenbufen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives class.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Fenbufen
  • Note
    Research use only, not for human use.
  • Brief Description
    Fenbufen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives class.
  • Description
    Fenbufen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives class.(In Vitro):Fenbufen (100-500 μM) improves the viability of apoptotic THP-1 cells treated with 25 μM Nigericin (HY-127019).(In Vivo):Fenbufenmay (1200 mg/kg; feed) does not cause gastric ulceration whilst inducing a near maximal inhibition of prostaglandin release in rats.Fenbufenmay (1200 mg/kg; p.o.; diet; for 10 days) blocks the hypertrophy of the heart but not that of the skeletal muscles.
  • In Vitro
    Fenbufen (100-500 μM) improves the viability of apoptotic THP-1 cells treated with 25 μM Nigericin (HY-127019).
  • In Vivo
    Fenbufenmay (1200 mg/kg; feed) does not cause gastric ulceration whilst inducing a near maximal inhibition of prostaglandin release in rats.Fenbufenmay (1200 mg/kg; p.o.; diet; for 10 days) blocks the hypertrophy of the heart but not that of the skeletal muscles. Animal Model:Male hooded Lister ratsDosage:1200 mg/kg Administration:Oral administration, diet, for 10 days Result:Significantly reduced Clenbuterol (2mg/kg)-induced hypertrophy of the heart.
  • Synonyms
    Fenbufen | Cinopal | Lederfen | CL-82204 | CL 82204 | CL82204
  • Pathway
    Endocrinology/Hormones
  • Target
    ATPase
  • Recptor
    ATP systhesis
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    36330-85-5
  • Formula Weight
    254.28
  • Molecular Formula
    C16H14O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    O=C(O)CCC(C1=CC=C(C2=CC=CC=C2)C=C1)=O
  • Chemical Name
    4-([1,1'-biphenyl]-4-yl)-4-oxobutanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yang Y, Gao H. Spectrochim Acta A Mol Biomol Spectrosc. 2013 Jan 15;101:119-26.
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