Cart
sales@molnova.com
Enfuvirtide
CAS No. 159519-65-0
Enfuvirtide ( )
Catalog No. M30031 CAS No. 159519-65-0
Enfuvirtide (INN) is an HIV fusion inhibitor, the first of a class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 51 | Get Quote |
|
| 10MG | 79 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
Biological Information
-
Product NameEnfuvirtide
-
NoteResearch use only, not for human use.
-
Brief DescriptionEnfuvirtide (INN) is an HIV fusion inhibitor, the first of a class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.
-
DescriptionEnfuvirtide (INN) is an HIV fusion inhibitor, the first of a class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.(In Vitro):A cell-cell fusion assay reveals that the effective concentration for achieving 50% inhibition (IC50) of Enfuvirtide is 23 ± 6 nM. IFN-λs (1, 2, or 3) or the antiretrovirals (AZT, Efavirenz, Indinavir, and Enfuvirtide) significantly inhibita the expression of HIV p24 antigen and Gag gene in macrophages. IFN-λs (1, 2, or 3) also enhanced the anti-HIV (Bal) effect of AZT, Efavirenz, Indinavir, and Enfuvirtide.(In Vivo):Enfuvirtide has a T1/2 of 3.8 h.
-
Synonyms
-
PathwayMicrobiology/Virology
-
TargetHIV
-
RecptorHIV fusion
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number159519-65-0
-
Formula Weight4491.9
-
Molecular FormulaC204H301N51O64
-
Purity>98% (HPLC)
-
SolubilityH2O : < 0.1 mg/mL (insoluble)
-
SMILES——
-
Chemical Name
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
Figueira TN, et al. Quantitative analysis of molecular partition towards lipid membranes using surface plasmon resonance. Sci Rep. 2017 Mar 30;7:45647.
molnova catalog
related products
-
Zalcitabine
A pyrimidine analog reverse transcriptase inhibitor (NRTI) for the treatment of HIV/AIDS.
-
ABX464
ABX464 (ABX-464, ABX 464) is a novel class of anti-HIV small molecule targeting Rev-mediated viral RNA biogenesis.
-
L-870810
A potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties.
