DDD85646 ( DDD-85646;DDD 85646 )

Catalog No. M27869 CAS No. 1215010-55-1

DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

DDD85646
Note

Research use only, not for human use.
Brief Description

DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.
Description

DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.
Synonyms

DDD-85646;DDD 85646
Pathway

Microbiology/Virology
Target

Parasite
Recptor

GABAA
Research Area

——
Indication

——

Chemical Information

CAS Number

1215010-55-1
Formula Weight

495.4
Molecular Formula

C21H24Cl2N6O2S
Purity

>98% (HPLC)
Solubility

——
SMILES

Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Quan Z, et al. Reactive oxygen species-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to cirsimaritin-induced apoptosis in human gallbladder carcinoma GBC-SD cells. Cancer Lett. 2010 Sep 28;295(2):252-9.

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