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Pyrimethamine
CAS No. 58-14-0
Pyrimethamine ( Pirimecidan;Pirimetamin;RP 4753 )
Catalog No. M15132 CAS No. 58-14-0
A synthetic derivative of ethyl-pyrimidine with potent antimalarial properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 34 | In Stock |
|
| 100MG | 47 | In Stock |
|
| 200MG | 70 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePyrimethamine
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NoteResearch use only, not for human use.
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Brief DescriptionA synthetic derivative of ethyl-pyrimidine with potent antimalarial properties.
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DescriptionA synthetic derivative of ethyl-pyrimidine with potent antimalarial properties; interferes with the regeneration of tetrahydrofolic acid from dihydrofolate by competitively inhibiting DHFR; has also been found to reduce the expression of SOD1.Parasite Infection Approved
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SynonymsPirimecidan;Pirimetamin;RP 4753
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PathwayMicrobiology/Virology
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TargetParasite
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RecptorDHFR
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Research AreaInfection
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IndicationParasite Infection
Chemical Information
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CAS Number58-14-0
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Formula Weight248.71
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Molecular FormulaC12H13ClN4
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl
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Chemical Name2,4-Pyrimidinediamine, 5-(4-chlorophenyl)-6-ethyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lange DJ, et al. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Apr;14(3):199-204.
2. Wright PD, et al. Neurosci Lett. 2010 Oct 4;482(3):188-92.
3. Martins-Duarte éS, et al. Exp Parasitol. 2013 Mar;133(3):294-9.
2. Wright PD, et al. Neurosci Lett. 2010 Oct 4;482(3):188-92.
3. Martins-Duarte éS, et al. Exp Parasitol. 2013 Mar;133(3):294-9.
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